Figure 5

Hematoxylin and eosin staining of lung sections after intratracheal instillation of fullerenes. Magnification ×100. (A) Negative control at 3 days (B) 0.2 mg fullerene-exposed lung at 3 days (C) 1 mg fullerene-exposed lung at 3 days (D) 0.2 mg nickel oxide-exposed lung at 3 days. (E) 1 mg fullerene-exposed lung at 1 week, (F) 1 mg fullerene-exposed lung at 1 month. Inflammation including mainly neutrophils was observed in the nickel oxide-exposed group. Mild inflammation was found in lung tissue in the 0.2 mg and 1 mg fullerene-exposed groups.