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Figure 7 | Particle and Fibre Toxicology

Figure 7

From: Cardiovascular and inflammatory effects of intratracheally instilled ambient dust from Augsburg, Germany, in spontaneously hypertensive rats (SHRs)

Figure 7

Side by side comparison of the lung and heart response of angiotensin converting enzyme (ACE; 5a), Endothelin-1 (ET-1; 5b), plasminogen activator inhibitor-1 (PAI-1; 5c), tissue factor (TF; 5d), vascular cell adhesion molecule-1(VCAM-1; 5e) and vascular endothelial growth factor (VEGF; 5f) following intratracheal instillation of sham and Augsburg particulate matter (PM 2.5 -AB, exposed) in spontaneously hypertensive rats (SHRs). Bars represent arithmetic mean values ± SE of sham (n = 6) and exposure groups (n = 6). †: Significantly (p < 0.05) lower than sham. ††: Significantly (p < 0.05) lower than sham and exposed at both day 1 and 3. *: Significantly (p < 0.05) higher than sham. **: Significantly (p < 0.05) higher than sham and 500 μg exposed at day1 both day 1 and 3. •: Significantly (p < 0.05) higher than 500 μg at 24 h. ••: Significantly (p < 0.05) higher than sham and 500 μg at day 1. ‡: Significantly (p < 0.05) higher than sham and exposed at day 1 and 3.

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