Skip to main content

Table 3 Chemical composition (g/L) of artificial biological fluids

From: Bioaccessibility, bioavailability and toxicity of commercially relevant iron- and chromium-based particles: in vitro studies with an inhalation perspective

Chemicals

ALF

pH 4.5

ASW

pH 6.5

GMB

pH 7.2

ATF

pH 8.0

MgCl2

0.050

-

0.095

-

NaCl

3.21

5.0

6.019

6.78

KCl

-

-

0.298

1.38

Na2HPO4

0.071

-

0.126

-

Na2SO4

0.039

-

0.063

-

CaCl2·2H2O

0.128

-

0.368

0.084

C2H3O2Na

-

-

0.574

-

NaHCO3

-

-

2.604

2.18

C6H5Na3O7·2H2O

0.077

-

0.097

-

KH2PO4

-

-

-

-

NaOH

6.00

-

-

-

C6H8O7

20.8

-

-

-

H2NCH2COOH

0.059

-

-

-

(NH2)2CO

-

1.0

-

-

CH3CHOHCO2H

-

1.0

-

-

C4H4O6Na2·2H2O

0.090

-

-

-

C3H5NaO3

0.085

-

-

-

C3H3O3Na

0.086

-

-

-

  1. Artificial lysosomal fluid (ALF), pH 4.5, artificial sweat (ASW) (according to EN1811), pH 6.5, Gamble's solution (GMB), pH 7.4, and artificial tear fluid (ATF), pH 8.0. Detailed information is given in [9, 10].