Effect of prolonged exposure to diesel engine exhaust on proinflammatory markers in different regions of the rat brain

Table 1 Basal levels of transcription factor activation, mRNA expression, and protein levels in different regions of the rat brain.

Brain Regions	Transcription Factor		RNA		Protein
	NF-κB	AP-1	TNF-α	TNFRI	TNFα	IL-1α
OB+T	+++	+++	+	+	+/++	++
Cortex	+	+	+	+	+	+
Striatum	+/++	+	+	+	++	++/+++
Hippocampus	++	++	+/++	+	++	++/+++
Cerebellum	++/+++	+	+/++	+	+/++	++/+++

For comparison purposes, values are designated as (+ = low; ++ = medium; or +++ = high) based on arbitrary assessment between groups for each marker.

ISSN: 1743-8977