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Table 2 Human studies linking air pollution exposure with atherosclerosis

From: Particulate matter and atherosclerosis: role of particle size, composition and oxidative stress

Study

Air pollutant

Evaluation of atherosclerosis

Major Findings

Reference

Kunzli et al

PM2.5

Ozone

CIMT

5.9% increased in CIMT per every 10 μg PM2.5/m3

[33]

Hoffmann et al

PM2.5

Distance to major road

CACS

Increased CAC scores with shorter distances to a major road

[34]

Diez Roux et al

PM10

PM2.5

CIMT

CACS

BAI

1-3% increase in CIMT per every 21 and 12.5 μg/m3 in PM10 and PM2.5 respectively

[35]

  1. CIMT = Carotid intima-media thickness, CACS = coronary artery calcium score,
  2. BAI = Brachial artery index.