Figure 7
From: Biodistribution and clearance of instilled carbon nanotubes in rat lung
MWCNT could induce alveolar macrophage (AM) apoptosis and apoptotic cells may be engulfed by other AM. TEM analysis of lung sections of rat instilled with 2 mg of MWCNT showed the presence of apoptotic macrophages. This observation is supporting by the quantification of mRNA of (B) Elmo 1, (C) Elmo 2 and (D) Dock 180 suggesting the capacity of macrophages to engulf apoptotic cells. Results are the mean of ± SD obtained on 6 rats. * Significantly different (p < 0.05) from control group.