Particle and Fibre Toxicology

Table 5 Percent lavagable vs non-lavagable TiO2 in the lung

From: Pulmonary response to intratracheal instillation of ultrafine versus fine titanium dioxide: role of particle surface area

Particle	7 Days post	42 Days post
UFTiO₂	19% lavagable	0% lavagable
	81% non-lavagable	100% non-lavagable
FTiO₂	91% lavagable	84% lavagable
	9% non-lavagable	16% non- lavagable

Values are for medium dose exposures (0.52 mg/rat vs 10.7 mg/rat for UFTiO₂ and FTiO₂, respectively, i.e., a surface area dose of 0.06 cm² particles/cm² alveolar epithelial surface).

Back to article page

ISSN: 1743-8977

Contact us

General enquiries: journalsubmissions@springernature.com