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Figure 4 | Particle and Fibre Toxicology

Figure 4

From: Interleukin-12 is not essential for silicosis in mice

Figure 4

Total lung collagen. The accumulation of collagen in the lung was assessed as the amount of OH-proline per right lung, with 5 mice in each group for each strain, exposure, and time point. The C57Bl/6 wild-type and the IL-12 KO mice exposed to silica had significantly more OH-Proline per right lung than the air- or TiO2-exposed mice at 14, 42, and 112 days after exposure (* = p < 0.01). The differences between the IL-12 KO mice and the wild-type mice exposed to silica did not reach significance.

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