From: Sub-chronic toxicity study in rats orally exposed to nanostructured silica
Group | Intended total silica exposure dose (mg/kg bw/day) | Â | Actual exposure dose | Â |
---|---|---|---|---|
Total silica (mg/kg bw/day) | Added silicaa(mg/kg/bw/day) | Silica in nano-size rangeb(mg/kg bw/day) | ||
SAS low | 100 | 222 | 83 | 33 |
SAS medium | 1000 | 942 | 819 | 328 |
SAS high | 2500 | 2142 | 2047 | 819 |
NM-202 low | 100 | 221 | 82 | 82 |
NM-202 medium | 500 | 537 | 405 | 405 |
NM-202 high | 1000 | 933 | 810 | 810 |
Negative control | 0 | 133 | 0 | <21 |