Effects of diesel exposure on lung function and inflammation biomarkers from airway and peripheral blood of healthy volunteers in a chamber study

Table 3 Effects of FA exposure and DE exposure on self-rated symptoms

	Before exposure	15 min exposure	75 min exposure	135 min exposure	Δ 15 min ^a	Δ 75 min ^a	Δ 135 min ^a
*FA exposure*
Runny nose	1.39±7.83	0.08±0.5	0.14±0.83	0.00±0.00	-1.31±7.86	-1.25±7.88	-1.39±7.83
Nasal congestion	1.69±7.99	0.53±1.18	0.61±1.87	0.36±1.36	-1.17±8.12	-1.08±8.21	-1.33±8.11
Throat irritation	1.66±7.46	1.00±5.01	0.11±0.46	0.08±0.50	-0.61±8.64	-1.50±7.03	-1.53±7.36
Chest tightness	--^*	--^*	--^*	0.14±0.83	--^*	--^*	0.14±0.83
*DE exposure*
Runny nose	2.86±10.91	1.97±10.09	1.44±7.66	1.69±8.34	-0.89±3.44	-1.42±4.86	-1.17±4.31
Nasal congestion	3.03±10.55	1.72±7.52	2.69±8.08	3.53±9.32	-1.31±4.33	-0.33±8.10	0.50±6.98
Throat irritation	2.31±6.96	1.06±2.27	4.00±8.64	6.06±12.11	-1.25±6.21	1.69±10.32	3.75±12.11^#
Chest tightness	0.28±1.67	0.17±0.74	0.17±0.74	0.56±2.29	-0.11±1.51	-0.11±1.85	0.28±2.88

Values are mean ± standard deviation (SD) using a visual analog scale.
DE, diesel exhaust; FA, filtered air.
^aΔ 15 min = 15 min of exposure – before exposure; Δ 75 min = 75 min of exposure – before exposure; Δ 135 min = 135 min of exposure – before exposure.
^*No symptoms were reported. ^#P <0.017 for DE exposure vs. FA exposure.

ISSN: 1743-8977