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Table 7 Cytology parameters in BALF after exposure to graphene

From: Comparative inhalation toxicity of multi-wall carbon nanotubes, graphene, graphite nanoplatelets and low surface carbon black

 

Study day 7

Study day 28

Concentration [mg/m3]

0.5

2.5

10

0.5

2.5

10

Total Cells

0.9

0.7

1.7

1.0

1.3

1.5**

Eosinophils

0.5

1.4

8.2**

1.7

2.3

0.0

Polymorphonuclear Neutrophils

1.2

7.5*

102.8**

1.0

3.0*

16.5**

Lymphocytes

3.0

4.2

33.4**

1.9

2.7

5.7**

Macrophages

0.8

0.6

0.6

1.0

1.2

1.2

  1. * Statistically significant, p < 0.05; ** statistically significant, p < 0.01.
  2. Differences are expressed as x-fold ratios compared to the concurrent control group.